Keynote Presentation: Linking Single-Cell Function to Multi-omic Analysis Using 'Lab on a Part...

Presented By: Dino Di Carlo, PhD

Speaker Biography: Dino Di Carlo is the Armond and Elena Hairapetian Professor of Bioengineering at UCLA, serial entrepreneur and inventor. He serves in academic leadership roles as the Vice Chair of the Bioengineering Department and Deputy Director of a National Science Foundation Engineering Research Center.

Webinar: Keynote Presentation: Linking Single-Cell Function to Multi-omic Analysis Using 'Lab on a Particle' Technology with Live Q&A

Webinar Abstract: We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cells based on secreted products for the discovery of antibodies, the development of cell lines producing recombinant products, and the selection of functional cells for cell therapies. Each cell and its secreted products can be analyzed using widely available flow cytometers and single-cell sequencing instruments, promising to democratize single-cell technologies. I will discuss our latest results linking the transcriptomes of single cells to the secreted products they produce. I will cover two example applications of this secretion encoded single-cell sequencing (SEC-seq) workflow.

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