Treating Sickle Cell Disease | Duke Health

Just five years ago, treatments for sickle cell disease were limited and primarily focused on alleviating pain. Thanks to recent advances, today there are alternatives in addition to Hydroxyurea for patients diagnosed with this complex disease including Endari (L-glutamine), Oxybryta (Voxelotor), and ADAKVEO (Crizanlizumab). Also, treatment is beginning earlier -- before pain and other complications occur. Here Duke hematologist, Nirmish Shah, MD, dispels myths surrounding sickle cell disease and discusses various new treatment options.

00:00 Intro
00:14 What treatments are there for sickle cell?
00:42 What is Hydroxyurea?
01:10 What is Endari or L-glutamine?
01:36 What is Oxybryta or Voxelotor?
01:51 What is ADAKVEO or Crizanlizumab?
02:17 What is a stem cell transplant?
02:50 Is there hope for people with sickle cell?